Chloroquine enhances the cytotoxicity of topotecan by inhibiting autophagy in lung cancer cells

Although the anti-malaria drug chloroquine (CQ) has been shown to enhance chemotherapy and radiation sensitivity in clinical trials, the potential mechanisms underlying this enhancement are still unclear. Here, we examined the relevant mechanisms by which the multipotent CQ enhanced the cytotoxicity...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Peng, Rui-Qing, Li, Dan-Dan, Ding, Ya, Wu, Xiao-Qi, Zeng, Yi-Xin, Zhu, Xiao-Feng, Zhang, Xiao-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012269/
https://www.ncbi.nlm.nih.gov/pubmed/21959046
http://dx.doi.org/10.5732/cjc.011.10056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012269/
https://www.ncbi.nlm.nih.gov/pubmed/21959046
http://dx.doi.org/10.5732/cjc.011.10056

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