Acute myeloid leukemia with t(7;21)(p22;q22) and 5q deletion: a case report and literature review

The gene RUNX1 at chromosome 21q22 encodes the alpha subunit of Core binding factor (CBF), a heterodimeric transcription factor involved in the development of normal hematopoiesis. Translocations of RUNX1 are seen in several types of leukemia with at least 21 identified partner genes. The cryptic t(...

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Detalles Bibliográficos
Autores principales: Ji, Jianling, Loo, Eric, Pullarkat, Sheeja, Yang, Lynn, Tirado, Carlos A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012275/
https://www.ncbi.nlm.nih.gov/pubmed/24646765
http://dx.doi.org/10.1186/2162-3619-3-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012275/
https://www.ncbi.nlm.nih.gov/pubmed/24646765
http://dx.doi.org/10.1186/2162-3619-3-8

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