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Acute myeloid leukemia with t(7;21)(p22;q22) and 5q deletion: a case report and literature review
The gene RUNX1 at chromosome 21q22 encodes the alpha subunit of Core binding factor (CBF), a heterodimeric transcription factor involved in the development of normal hematopoiesis. Translocations of RUNX1 are seen in several types of leukemia with at least 21 identified partner genes. The cryptic t(...
Autores principales: | Ji, Jianling, Loo, Eric, Pullarkat, Sheeja, Yang, Lynn, Tirado, Carlos A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012275/ https://www.ncbi.nlm.nih.gov/pubmed/24646765 http://dx.doi.org/10.1186/2162-3619-3-8 |
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