Possible impact of the CYP2D6*10 polymorphism on the nonlinear pharmacokinetic parameter estimates of paroxetine in Japanese patients with major depressive disorders

It has been suggested that the reduced function allele with reduced cytochrome P450 (CYP) 2D6 activity, CYP2D6*10, is associated with the interindividual differences in the plasma paroxetine concentrations, but there is no data presently available regarding the influence of the CYP2D6*10 polymorphis...

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Detalles Bibliográficos
Autores principales: Saruwatari, Junji, Nakashima, Hiroo, Tsuchimine, Shoko, Nishimura, Miki, Ogusu, Naoki, Yasui-Furukori, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012347/
https://www.ncbi.nlm.nih.gov/pubmed/24868171
http://dx.doi.org/10.2147/PGPM.S60747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012347/
https://www.ncbi.nlm.nih.gov/pubmed/24868171
http://dx.doi.org/10.2147/PGPM.S60747

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