Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides

As the concentrations of highly consumed nutrients, particularly glucose, are generally lower in tumours than in normal tissues(1,2), cancer cells must adapt their metabolism to the tumour microenvironment. A better understanding of these adaptations might reveal cancer cell liabilities that can be...

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Detalles Bibliográficos
Autores principales: Birsoy, Kıvanç, Possemato, Richard, Lorbeer, Franziska K., Bayraktar, Erol C., Thiru, Prathapan, Yucel, Burcu, Wang, Tim, Chen, Walter W., Clish, Clary B., Sabatini, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012432/
https://www.ncbi.nlm.nih.gov/pubmed/24670634
http://dx.doi.org/10.1038/nature13110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012432/
https://www.ncbi.nlm.nih.gov/pubmed/24670634
http://dx.doi.org/10.1038/nature13110

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