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The Marine Fungal Metabolite, Dicitrinone B, Induces A375 Cell Apoptosis through the ROS-Related Caspase Pathway

Dicitrinone B, a rare carbon-bridged citrinin dimer, was isolated from the marine-derived fungus, Penicillium citrinum. It was reported to have antitumor effects on tumor cells previously; however, the details of the mechanism remain unclear. In this study, we found that dicitrinone B inhibited the...

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Detalles Bibliográficos
Autores principales: Chen, Li, Gong, Mei-Wei, Peng, Zhen-Fei, Zhou, Tong, Ying, Min-Gang, Zheng, Qiu-Hong, Liu, Qin-Ying, Zhang, Qi-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012433/
https://www.ncbi.nlm.nih.gov/pubmed/24699111
http://dx.doi.org/10.3390/md12041939