Cargando…

The Marine Fungal Metabolite, Dicitrinone B, Induces A375 Cell Apoptosis through the ROS-Related Caspase Pathway

Dicitrinone B, a rare carbon-bridged citrinin dimer, was isolated from the marine-derived fungus, Penicillium citrinum. It was reported to have antitumor effects on tumor cells previously; however, the details of the mechanism remain unclear. In this study, we found that dicitrinone B inhibited the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Li, Gong, Mei-Wei, Peng, Zhen-Fei, Zhou, Tong, Ying, Min-Gang, Zheng, Qiu-Hong, Liu, Qin-Ying, Zhang, Qi-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012433/ https://www.ncbi.nlm.nih.gov/pubmed/24699111 http://dx.doi.org/10.3390/md12041939

Ejemplares similares

The marine natural product, dicitrinone B, induces apoptosis through autophagy blockade in breast cancer
por: Liu, Qinying, et al.
Publicado: (2022)

Norcantharidin Induces Human Melanoma A375-S2 Cell Apoptosis through Mitochondrial and Caspase Pathways
por: An, Wei-wei, et al.
Publicado: (2004)

Mechanism of Lakoochin A Inducing Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS and MAPKs Pathway
por: Peng, Kuo-Ti, et al.
Publicado: (2018)

Cudraflavone C Induces Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS Production and MAPK Activation
por: Lee, Chiang-Wen, et al.
Publicado: (2017)

Synthesis and Antitumor Activities of Derivatives of the Marine Mangrove Fungal Metabolite Deoxybostrycin
por: Chen, Hong, et al.
Publicado: (2012)

The BH3 mimetic (±) gossypol induces ROS-independent apoptosis and mitochondrial dysfunction in human A375 melanoma cells in vitro
por: Haasler, Lisa, et al.
Publicado: (2021)

The Roles of ROS and Caspases in TRAIL-Induced Apoptosis and Necroptosis in Human Pancreatic Cancer Cells
por: Zhang, Min, et al.
Publicado: (2015)

Oxeiptosis – a ROS induced caspase-independent apoptosis-like cell death pathway
por: Holze, Cathleen, et al.
Publicado: (2017)

ROS Regulate Caspase-Dependent Cell Delamination without Apoptosis in the Drosophila Pupal Notum
por: Fujisawa, Yuya, et al.
Publicado: (2020)

Acetylshikonin Sensitizes Hepatocellular Carcinoma Cells to Apoptosis through ROS-Mediated Caspase Activation
por: Hong, Ming, et al.
Publicado: (2019)

Caspase-dependent signaling underlies glioblastoma cell death in response to the fungal metabolite, fusarochromanone
por: MAHDAVIAN, ELAHE, et al.
Publicado: (2014)

Proteomic Investigation of the Sinulariolide-Treated Melanoma Cells A375: Effects on the Cell Apoptosis through Mitochondrial-Related Pathway and Activation of Caspase Cascade
por: Li, Hsing-Hui, et al.
Publicado: (2013)

Triclosan induces ROS-dependent cell death and autophagy in A375 melanoma cells
por: Jin, Jing, et al.
Publicado: (2020)

Mycoplasma ovipneumoniae induces caspase-8-dependent extrinsic apoptosis and p53- and ROS-dependent intrinsic apoptosis in murine alveolar macrophages
por: Chen, Jing, et al.
Publicado: (2021)

Pardaxin, an Antimicrobial Peptide, Triggers Caspase-Dependent and ROS-Mediated Apoptosis in HT-1080 Cells
por: Huang, Tsui-Chin, et al.
Publicado: (2011)

Effects Of Adenosine On Apoptosis Of Ovarian Cancer A2780 Cells Via ROS And Caspase Pathways
por: Xia, Bing, et al.
Publicado: (2019)

Simvastatin induces pyroptosis via ROS/caspase-1/GSDMD pathway in colon cancer
por: Xie, Wei, et al.
Publicado: (2023)

The neuroprotective mechanism of 2-arachidonoylglycerol 2-AG against non-caspase-dependent apoptosis in mice hippocampal neurons following MCAO
por: Zhong, He-Ying, et al.
Publicado: (2019)

Hinokiflavone induces apoptosis via activating mitochondrial ROS/JNK/caspase pathway and inhibiting NF‐κB activity in hepatocellular carcinoma
por: Mu, Wan, et al.
Publicado: (2020)

Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines
por: Prabhu, Kirti S., et al.
Publicado: (2019)

Effects of Adenosine on Apoptosis of Ovarian Cancer A2780 Cells via ROS and Caspase Pathways [Corrigendum]
Publicado: (2020)

Phenethyl Isothiocyanate Induces Apoptosis Through ROS Generation and Caspase-3 Activation in Cervical Cancer Cells
por: Shoaib, Shoaib, et al.
Publicado: (2021)

[6]-Gingerol induces Caspase-Dependent Apoptosis in Bladder Cancer cells via MAPK and ROS Signaling
por: Choi, Na Ri, et al.
Publicado: (2022)

Triggering Apoptotic Death of Human Malignant Melanoma A375.S2 Cells by Bufalin: Involvement of Caspase Cascade-Dependent and Independent Mitochondrial Signaling Pathways
por: Hsiao, Yu-Ping, et al.
Publicado: (2012)

Can Some Marine-Derived Fungal Metabolites Become Actual Anticancer Agents?
por: Gomes, Nelson G. M., et al.
Publicado: (2015)

ROS Induced by KillerRed Targeting Mitochondria (mtKR) Enhances Apoptosis Caused by Radiation via Cyt c/Caspase-3 Pathway
por: Li, Xin, et al.
Publicado: (2019)

The Induction of Apoptosis in A375 Malignant Melanoma Cells by Sutherlandia frutescens
por: van der Walt, Nicola B., et al.
Publicado: (2016)

Shikonin Inhibits the Proliferation of Human Lens Epithelial Cells by Inducing Apoptosis through ROS and Caspase-Dependent Pathway
por: Huang, Wan-Rong, et al.
Publicado: (2014)

Induction of apoptosis by piperine in human cervical adenocarcinoma via ROS mediated mitochondrial pathway and caspase-3 activation
por: Jafri, Asif, et al.
Publicado: (2019)

Osthole Induces Apoptosis and Caspase-3/GSDME-Dependent Pyroptosis via NQO1-Mediated ROS Generation in HeLa Cells
por: Wang, Juan, et al.
Publicado: (2022)

The Marine Fungal Metabolite, AD0157, Inhibits Angiogenesis by Targeting the Akt Signaling Pathway
por: García-Caballero, Melissa, et al.
Publicado: (2014)

Marine endophytic fungal metabolites: A whole new world of pharmaceutical therapy exploration
por: El-Bondkly, Esraa Ahmed Mohamed, et al.
Publicado: (2021)

Sulfur-Containing Metabolites from Marine and Terrestrial Fungal Sources: Origin, Structures, and Bioactivities
por: Liu, Zhaoming, et al.
Publicado: (2022)

Effect of hypoxia factors gene silencing on ROS production and metabolic status of A375 malignant melanoma cells
por: Špaková, Ivana, et al.
Publicado: (2021)

Pathological apoptosis by xanthurenic acid, a tryptophan metabolite: activation of cell caspases but not cytoskeleton breakdown
por: Malina, Halina Z, et al.
Publicado: (2001)

Duck Plague Virus Promotes DEF Cell Apoptosis by Activating Caspases, Increasing Intracellular ROS Levels and Inducing Cell Cycle S-Phase Arrest
por: Zhao, Chuankuo, et al.
Publicado: (2019)

HSP27 Inhibits Homocysteine-Induced Endothelial Apoptosis by Modulation of ROS Production and Mitochondrial Caspase-Dependent Apoptotic Pathway
por: Tian, Xin, et al.
Publicado: (2016)

ROS-dependent Bax/Bcl2 and caspase 3 pathway-mediated apoptosis induced by zineb in human keratinocyte cells
por: Ali, Daoud, et al.
Publicado: (2018)

Effects of ginsenoside Rg3 on apoptosis in A375.S2 melanoma cells
por: Kim, Joo Hyoung, et al.
Publicado: (2019)

Shikonin promotes adriamycin-induced apoptosis by upregulating caspase-3 and caspase-8 in osteosarcoma
por: Yang, Qing, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_9e28cqfot9nsr1bg1tts99l3if