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Synthesis and Evaluation of Some New Aza-B-homocholestane Derivatives as Anticancer Agents

Using analogues of some marine steroidal oximes as precursors, a series of aza-B-homocholestane derivatives possessing different substituted groups at the 3-position of the steroidal nucleus were synthesized. Their biological activity against cancer cell proliferation was determined with multiple ca...

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Detalles Bibliográficos
Autores principales: Huang, Yanmin, Cui, Jianguo, Chen, Sijing, Lin, Qifu, Song, Huacan, Gan, Chunfang, Su, Bin, Zhou, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012452/
https://www.ncbi.nlm.nih.gov/pubmed/24670533
http://dx.doi.org/10.3390/md12041715