Action of Clathrodin and Analogues on Voltage-Gated Sodium Channels

Clathrodin is a marine alkaloid and believed to be a modulator of voltage-gated sodium (Na(V) ) channels. Since there is an urgent need for small molecule Na(V) channel ligands as novel therapeutics, clathrodin could represent an interesting lead compound. Therefore, clathrodin was reinvestigated fo...

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Detalles Bibliográficos
Autores principales: Peigneur, Steve, Žula, Aleš, Zidar, Nace, Chan-Porter, Fiona, Kirby, Robert, Madge, David, Ilaš, Janez, Kikelj, Danijel, Tytgat, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012458/
https://www.ncbi.nlm.nih.gov/pubmed/24714127
http://dx.doi.org/10.3390/md12042132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012458/
https://www.ncbi.nlm.nih.gov/pubmed/24714127
http://dx.doi.org/10.3390/md12042132

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