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Action of Clathrodin and Analogues on Voltage-Gated Sodium Channels
Clathrodin is a marine alkaloid and believed to be a modulator of voltage-gated sodium (Na(V) ) channels. Since there is an urgent need for small molecule Na(V) channel ligands as novel therapeutics, clathrodin could represent an interesting lead compound. Therefore, clathrodin was reinvestigated fo...
Autores principales: | Peigneur, Steve, Žula, Aleš, Zidar, Nace, Chan-Porter, Fiona, Kirby, Robert, Madge, David, Ilaš, Janez, Kikelj, Danijel, Tytgat, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012458/ https://www.ncbi.nlm.nih.gov/pubmed/24714127 http://dx.doi.org/10.3390/md12042132 |
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