Seven New and Two Known Lipopeptides as well as Five Known Polyketides: The Activated Production of Silent Metabolites in a Marine-Derived Fungus by Chemical Mutagenesis Strategy Using Diethyl Sulphate

AD-2-1 is an antitumor fungal mutant obtained by diethyl sulfate mutagenesis of a marine-derived Penicillium purpurogenum G59. The G59 strain originally did not produce any metabolites with antitumor activities in MTT assays using K562 cells. Tracing newly produced metabolites under guidance of MTT...

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Detalles Bibliográficos
Autores principales: Wu, Chang-Jing, Li, Chang-Wei, Cui, Cheng-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012460/
https://www.ncbi.nlm.nih.gov/pubmed/24686557
http://dx.doi.org/10.3390/md12041815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012460/
https://www.ncbi.nlm.nih.gov/pubmed/24686557
http://dx.doi.org/10.3390/md12041815

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