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Design, Synthesis and Biological Evaluation of Tasiamide Analogues as Tumor Inhibitors
Eighteen analogues of the marine cytotoxic linear peptide tasiamide were designed, synthesized and screened for their inhibitory activities against the growth of human nasopharyngeal carcinoma (KB) and human non-small cell lung tumor (A549) cell lines. The results indicated that minor modifications...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012464/ https://www.ncbi.nlm.nih.gov/pubmed/24759000 http://dx.doi.org/10.3390/md12042308 |