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Transcription factor Achaete-Scute homologue 2 initiates T follicular helper cell development
In immune responses, activated T cells migrate to B cell follicles and develop to T follicular helper (Tfh) cells, a new subset of CD4(+) T cells specialized in providing help to B lymphocytes in the induction of germinal centers (1,2). Although Bcl6 has been shown to be essential in Tfh cell functi...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012617/ https://www.ncbi.nlm.nih.gov/pubmed/24463518 http://dx.doi.org/10.1038/nature12910 |