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Arsenic-induced sub-lethal stress reprograms human bronchial epithelial cells to CD61¯ cancer stem cells

In the present report, we demonstrate that sub-lethal stress induced by consecutive exposure to 0.25 μM arsenic (As(3+)) for six months can trigger reprogramming of the human bronchial epithelial cell (BEAS-2B) to form cancer stem cells (CSCs) without forced introduction of the stemness transcriptio...

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Detalles Bibliográficos
Autores principales: Chang, Qingshan, Chen, Bailing, Thakur, Chitra, Lu, Yongju, Chen, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012730/
https://www.ncbi.nlm.nih.gov/pubmed/24675390