Endothelial integrin α3β1 stabilizes carbohydrate-mediated tumor/endothelial cell adhesion and induces macromolecular signaling complex formation at the endothelial cell membrane

Blood borne metastatic tumor cell adhesion to endothelial cells constitutes a critical rate-limiting step in hematogenous cancer metastasis. Interactions between cancer associated carbohydrate Thomsen-Friedenreich antigen (TF-Ag) and endothelium-expressed galectin-3 (Gal-3) have been identified as t...

Descripción completa

Detalles Bibliográficos
Autores principales: Glinskii, Olga V., Li, Feng, Wilson, Landon S., Barnes, Stephen, Rittenhouse-Olson, Kate, Barchi, Joseph J., Pienta, Kenneth J., Glinsky, Vladislav V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012737/
https://www.ncbi.nlm.nih.gov/pubmed/24675526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012737/
https://www.ncbi.nlm.nih.gov/pubmed/24675526

Ejemplares similares