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Phospholipase A/Acyltransferase enzyme activity of H-rev107 inhibits the H-RAS signaling pathway

BACKGROUND: H-rev107, also called HRASLS3 or PLA2G16, is a member of the HREV107 type II tumor suppressor gene family. Previous studies showed that H-rev107 exhibits phospholipase A/acyltransferase (PLA/AT) activity and downregulates H-RAS expression. However, the mode of action and the site of inhi...

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Detalles Bibliográficos
Autores principales: Wang, Chun-Hua, Shyu, Rong-Yaun, Wu, Chang-Chieh, Tsai, Tzung-Chieh, Wang, Lu-Kai, Chen, Mao-Liang, Jiang, Shun-Yuan, Tsai, Fu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012743/
https://www.ncbi.nlm.nih.gov/pubmed/24884338
http://dx.doi.org/10.1186/1423-0127-21-36