Interaction between Cell-Penetrating Peptides and Acid-Sensitive Anionic Oligopeptides as a Model for the Design of Targeted Drug Carriers

[Image: see text] Overcoming the nonspecific cellular uptake of cell-penetrating peptides (CPPs) is a major hurdle in their clinical application. Using pH as the activation switch, histidine-glutamic acid (HE) dipeptide repeats were fused to CPPs to trigger the membrane-penetrating activity at mildl...

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Detalles Bibliográficos
Autores principales: Sun, Chunmeng, Shen, Wei-Chiang, Tu, Jiasheng, Zaro, Jennica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012841/
https://www.ncbi.nlm.nih.gov/pubmed/24697211
http://dx.doi.org/10.1021/mp400747k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012841/
https://www.ncbi.nlm.nih.gov/pubmed/24697211
http://dx.doi.org/10.1021/mp400747k

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