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A Lack of Immune System Genes Causes Loss in High Frequency Hearing but Does Not Disrupt Cochlear Synapse Maturation in Mice

Early cochlear development is marked by an exuberant outgrowth of neurites that innervate multiple targets. The establishment of mature cochlear neural circuits is, however, dependent on the pruning of inappropriate axons and synaptic connections. Such refinement also occurs in the central nervous s...

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Detalles Bibliográficos
Autores principales: Calton, Melissa A., Lee, Dasom, Sundaresan, Srividya, Mendus, Diana, Leu, Rose, Wangsawihardja, Felix, Johnson, Kenneth R., Mustapha, Mirna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012943/
https://www.ncbi.nlm.nih.gov/pubmed/24804771
http://dx.doi.org/10.1371/journal.pone.0094549