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A Lack of Immune System Genes Causes Loss in High Frequency Hearing but Does Not Disrupt Cochlear Synapse Maturation in Mice
Early cochlear development is marked by an exuberant outgrowth of neurites that innervate multiple targets. The establishment of mature cochlear neural circuits is, however, dependent on the pruning of inappropriate axons and synaptic connections. Such refinement also occurs in the central nervous s...
Autores principales: | Calton, Melissa A., Lee, Dasom, Sundaresan, Srividya, Mendus, Diana, Leu, Rose, Wangsawihardja, Felix, Johnson, Kenneth R., Mustapha, Mirna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012943/ https://www.ncbi.nlm.nih.gov/pubmed/24804771 http://dx.doi.org/10.1371/journal.pone.0094549 |
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