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The Dimerization Domain in DapE Enzymes Is required for Catalysis

The emergence of antibiotic-resistant bacterial strains underscores the importance of identifying new drug targets and developing new antimicrobial compounds. Lysine and meso-diaminopimelic acid are essential for protein production and bacterial peptidoglycan cell wall remodeling and are synthesized...

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Detalles Bibliográficos
Autores principales: Nocek, Boguslaw, Starus, Anna, Makowska-Grzyska, Magdalena, Gutierrez, Blanca, Sanchez, Stephen, Jedrzejczak, Robert, Mack, Jamey C., Olsen, Kenneth W., Joachimiak, Andrzej, Holz, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012986/
https://www.ncbi.nlm.nih.gov/pubmed/24806882
http://dx.doi.org/10.1371/journal.pone.0093593