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Age-Related Decrease of Meiotic Cohesins in Human Oocytes

Aneuploidy in fetal chromosomes is one of the causes of pregnancy loss and of congenital birth defects. It is known that the frequency of oocyte aneuploidy increases with the human maternal age. Recent data have highlighted the contribution of cohesin complexes in the correct segregation of meiotic...

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Detalles Bibliográficos
Autores principales: Tsutsumi, Makiko, Fujiwara, Reiko, Nishizawa, Haruki, Ito, Mayuko, Kogo, Hiroshi, Inagaki, Hidehito, Ohye, Tamae, Kato, Takema, Fujii, Takuma, Kurahashi, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013030/
https://www.ncbi.nlm.nih.gov/pubmed/24806359
http://dx.doi.org/10.1371/journal.pone.0096710