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Sets of Covariant Residues Modulate the Activity and Thermal Stability of GH1 β-Glucosidases
The statistical coupling analysis of 768 β-glucosidases from the GH1 family revealed 23 positions in which the amino acid frequencies are coupled. The roles of these covariant positions in terms of the properties of β-glucosidases were investigated by alanine-screening mutagenesis using the fall arm...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013033/ https://www.ncbi.nlm.nih.gov/pubmed/24804841 http://dx.doi.org/10.1371/journal.pone.0096627 |