Fast Skeletal Muscle Troponin Activator tirasemtiv Increases Muscle Function and Performance in the B6SJL-SOD1(G93A) ALS Mouse Model

Amyotrophic Lateral Sclerosis (ALS) is a motor neuron disease characterized by progressive motor neuron loss resulting in muscle atrophy, declining muscle function, and eventual paralysis. Patients typically die from respiratory failure 3 to 5 years from the onset of symptoms. Tirasemtiv is a fast s...

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Detalles Bibliográficos
Autores principales: Hwee, Darren T., Kennedy, Adam, Ryans, Julie, Russell, Alan J., Jia, Zhiheng, Hinken, Aaron C., Morgans, David J., Malik, Fady I., Jasper, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013064/
https://www.ncbi.nlm.nih.gov/pubmed/24805850
http://dx.doi.org/10.1371/journal.pone.0096921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013064/
https://www.ncbi.nlm.nih.gov/pubmed/24805850
http://dx.doi.org/10.1371/journal.pone.0096921

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