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Functional Characterization Improves Associations between Rare Non-Synonymous Variants in CHRNB4 and Smoking Behavior
Smoking is the leading cause of preventable death worldwide. Accordingly, effort has been devoted to determining the genetic variants that contribute to smoking risk. Genome-wide association studies have identified several variants in nicotinic acetylcholine receptor genes that contribute to nicotin...
Autores principales: | Haller, Gabe, Li, Ping, Esch, Caroline, Hsu, Simon, Goate, Alison M., Steinbach, Joe Henry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013067/ https://www.ncbi.nlm.nih.gov/pubmed/24804708 http://dx.doi.org/10.1371/journal.pone.0096753 |
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