FMRP S499 Is Phosphorylated Independent of mTORC1-S6K1 Activity

Hyperactive mammalian target of rapamycin (mTOR) is associated with cognitive deficits in several neurological disorders including tuberous sclerosis complex (TSC). The phosphorylation of the mRNA-binding protein FMRP reportedly depends on mTOR complex 1 (mTORC1) activity via p70 S6 kinase 1 (S6K1)....

Descripción completa

Detalles Bibliográficos
Autores principales: Bartley, Christopher M., O’Keefe, Rachel A., Bordey, Angélique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013076/
https://www.ncbi.nlm.nih.gov/pubmed/24806451
http://dx.doi.org/10.1371/journal.pone.0096956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013076/
https://www.ncbi.nlm.nih.gov/pubmed/24806451
http://dx.doi.org/10.1371/journal.pone.0096956

Ejemplares similares