Real-World Efficiency of Pharmacogenetic Screening for Carbamazepine-Induced Severe Cutaneous Adverse Reactions

OBJECTIVES: We evaluated the cost and efficiency of routine HLA-B*15∶02 screening to prevent carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (CBZ-SJS/TEN) in Hong Kong. METHODS: Data were extracted from patients who commenced CBZ as the first-ever AED treatment or teste...

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Detalles Bibliográficos
Autores principales: Chen, Zhibin, Liew, Danny, Kwan, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013087/
https://www.ncbi.nlm.nih.gov/pubmed/24806465
http://dx.doi.org/10.1371/journal.pone.0096990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013087/
https://www.ncbi.nlm.nih.gov/pubmed/24806465
http://dx.doi.org/10.1371/journal.pone.0096990

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