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A Regulatory Transcriptional Loop Controls Proliferation and Differentiation in Drosophila Neural Stem Cells
Neurogenesis is initiated by a set of basic Helix-Loop-Helix (bHLH) transcription factors that specify neural progenitors and allow them to generate neurons in multiple rounds of asymmetric cell division. The Drosophila Daughterless (Da) protein and its mammalian counterparts (E12/E47) act as hetero...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013126/ https://www.ncbi.nlm.nih.gov/pubmed/24804774 http://dx.doi.org/10.1371/journal.pone.0097034 |