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A Regulatory Transcriptional Loop Controls Proliferation and Differentiation in Drosophila Neural Stem Cells

Neurogenesis is initiated by a set of basic Helix-Loop-Helix (bHLH) transcription factors that specify neural progenitors and allow them to generate neurons in multiple rounds of asymmetric cell division. The Drosophila Daughterless (Da) protein and its mammalian counterparts (E12/E47) act as hetero...

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Detalles Bibliográficos
Autores principales: Yasugi, Tetsuo, Fischer, Anja, Jiang, Yanrui, Reichert, Heinrich, Knoblich, Juergen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013126/
https://www.ncbi.nlm.nih.gov/pubmed/24804774
http://dx.doi.org/10.1371/journal.pone.0097034

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