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Progranulin Gene Delivery Protects Dopaminergic Neurons in a Mouse Model of Parkinson’s Disease

Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by tremor, rigidity and akinesia/bradykinesia resulting from the progressive loss of nigrostriatal dopaminergic neurons. To date, only symptomatic treatment is available for PD patients, with no effective means of slo...

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Detalles Bibliográficos
Autores principales: Van Kampen, Jackalina M., Baranowski, David, Kay, Denis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013129/
https://www.ncbi.nlm.nih.gov/pubmed/24804730
http://dx.doi.org/10.1371/journal.pone.0097032