Specific Epiblast Loss and Hypoblast Impairment in Cattle Embryos Sensitized to Survival Signalling by Ubiquitous Overexpression of the Proapoptotic Gene BAD

Early embryonic lethality is common, particularly in dairy cattle. We made cattle embryos more sensitive to environmental stressors by raising the threshold of embryo survival signaling required to overcome the deleterious effects of overexpressing the proapoptotic protein BAD. Two primary fibroblas...

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Detalles Bibliográficos
Autores principales: van Leeuwen, Jessica, Berg, Debra K., Smith, Craig S., Wells, David N., Pfeffer, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013130/
https://www.ncbi.nlm.nih.gov/pubmed/24806443
http://dx.doi.org/10.1371/journal.pone.0096843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013130/
https://www.ncbi.nlm.nih.gov/pubmed/24806443
http://dx.doi.org/10.1371/journal.pone.0096843

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