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Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells
The condensin complex is required for chromosome condensation during mitosis; however, the role of this complex during interphase is unclear. Neuroblastoma is the most common extracranial solid tumor of childhood, and it is often lethal. In human neuroblastoma, MYCN gene amplification is correlated...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013162/ https://www.ncbi.nlm.nih.gov/pubmed/24553121 http://dx.doi.org/10.4161/cc.27983 |