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Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells

The condensin complex is required for chromosome condensation during mitosis; however, the role of this complex during interphase is unclear. Neuroblastoma is the most common extracranial solid tumor of childhood, and it is often lethal. In human neuroblastoma, MYCN gene amplification is correlated...

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Detalles Bibliográficos
Autores principales: Murakami-Tonami, Yuko, Kishida, Satoshi, Takeuchi, Ichiro, Katou, Yuki, Maris, John M, Ichikawa, Hitoshi, Kondo, Yutaka, Sekido, Yoshitaka, Shirahige, Katsuhiko, Murakami, Hiroshi, Kadomatsu, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013162/
https://www.ncbi.nlm.nih.gov/pubmed/24553121
http://dx.doi.org/10.4161/cc.27983