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Hepatitis B virus X protein regulates the mEZH2 promoter via the E2F1-binding site in AML12 cells

Histone lysine methyltransferase EZH2 has been reported to be frequently overexpressed in hepatocellular carcinoma (HCC) tissues and associated with hepatocarcinogenesis. However, the exact mechanism of EZH2 up-regulation in HCC has not been determined. In this study, we used murine hepatocyte AML12...

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Detalles Bibliográficos
Autores principales: Shi, Xiao-Yan, Zhang, Ying-Ying, Zhou, Xiao-Wei, Lu, Jian-Sheng, Guo, Ze-Kun, Huang, Pei-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013354/
https://www.ncbi.nlm.nih.gov/pubmed/21439249
http://dx.doi.org/10.5732/cjc.010.10437