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Late-Onset Alzheimer’s Disease Genes and the Potentially Implicated Pathways

Late-onset Alzheimer’s disease (LOAD) is a devastating neurodegenerative disease with no effective treatment or cure. In addition to APOE, recent large genome-wide association studies have identified variation in over 20 loci that contribute to disease risk: CR1, BIN1, INPP5D, MEF2C, TREM2, CD2AP, H...

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Detalles Bibliográficos
Autores principales: Rosenthal, Samantha L., Kamboh, M. Ilyas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013444/
https://www.ncbi.nlm.nih.gov/pubmed/24829845
http://dx.doi.org/10.1007/s40142-014-0034-x