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The −930A>G polymorphism of the CYBA gene is associated with premature coronary artery disease. A case–control study and gene–risk factors interactions

Reactive oxygen species (ROS) are involved in the pathogenesis of atherosclerosis and coronary artery disease (CAD). NADPH oxidases are the main source of ROS in the vasculature. p22phox is a critical component of vascular NADPH oxidases and is encoded by the CYBA (cytochrome b(245) alpha) gene. The...

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Detalles Bibliográficos
Autores principales: Niemiec, Pawel, Nowak, Tomasz, Iwanicki, Tomasz, Krauze, Jolanta, Gorczynska-Kosiorz, Sylwia, Grzeszczak, Wladyslaw, Ochalska-Tyka, Anna, Zak, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013450/
https://www.ncbi.nlm.nih.gov/pubmed/24477591
http://dx.doi.org/10.1007/s11033-014-3191-9