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Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations
The cloaca is temporally formed and eventually divided by the urorectal septum (URS) during urogenital and anorectal organ development. Although congenital malformations, such as anorectal malformations (ARMs), are frequently observed during this process, the underlying pathogenic mechanisms remain...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013517/ https://www.ncbi.nlm.nih.gov/pubmed/24632946 http://dx.doi.org/10.1038/cdd.2014.21 |