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Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations

The cloaca is temporally formed and eventually divided by the urorectal septum (URS) during urogenital and anorectal organ development. Although congenital malformations, such as anorectal malformations (ARMs), are frequently observed during this process, the underlying pathogenic mechanisms remain...

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Detalles Bibliográficos
Autores principales: Miyagawa, S, Harada, M, Matsumaru, D, Tanaka, K, Inoue, C, Nakahara, C, Haraguchi, R, Matsushita, S, Suzuki, K, Nakagata, N, Ng, R C-L, Akita, K, Lui, V C-H, Yamada, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013517/
https://www.ncbi.nlm.nih.gov/pubmed/24632946
http://dx.doi.org/10.1038/cdd.2014.21