Regulation of the localisation and function of the oncogene LYRIC/AEG‐1 by ubiquitination at K486 and K491

The pivotal role of LYRIC/AEG‐1 in malignant transformation, tumourigenesis and chemo‐resistance has previously been demonstrated in different cell types and sub‐cellular compartments. The localisation of LYRIC/AEG‐1 appears crucial to its function and is regulated by three lysine‐rich nuclear local...

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Detalles Bibliográficos
Autores principales: Luxton, Hayley J., Barnouin, Karin, Kelly, Gavin, Hanrahan, Sarah, Totty, Nick, Neal, David E., Whitaker, Hayley C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013555/
https://www.ncbi.nlm.nih.gov/pubmed/24529480
http://dx.doi.org/10.1016/j.molonc.2014.01.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013555/
https://www.ncbi.nlm.nih.gov/pubmed/24529480
http://dx.doi.org/10.1016/j.molonc.2014.01.009

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