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Regulation of the localisation and function of the oncogene LYRIC/AEG‐1 by ubiquitination at K486 and K491
The pivotal role of LYRIC/AEG‐1 in malignant transformation, tumourigenesis and chemo‐resistance has previously been demonstrated in different cell types and sub‐cellular compartments. The localisation of LYRIC/AEG‐1 appears crucial to its function and is regulated by three lysine‐rich nuclear local...
Autores principales: | Luxton, Hayley J., Barnouin, Karin, Kelly, Gavin, Hanrahan, Sarah, Totty, Nick, Neal, David E., Whitaker, Hayley C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013555/ https://www.ncbi.nlm.nih.gov/pubmed/24529480 http://dx.doi.org/10.1016/j.molonc.2014.01.009 |
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