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Transgene IL-6 Enhances DC-Stimulated CTL Responses by Counteracting CD4(+)25(+)Foxp3(+) Regulatory T Cell Suppression via IL-6-Induced Foxp3 Downregulation

Dendritic cells (DCs), the most potent antigen-presenting cells have been extensively applied in clinical trials for evaluation of antitumor immunity. However, the efficacy of DC-mediated cancer vaccines is still limited as they are unable to sufficiently break the immune tolerance. In this study, w...

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Detalles Bibliográficos
Autores principales:	Bhanumathy, Kalpana Kalyanasundaram, Zhang, Bei, Ahmed, Khawaja Ashfaque, Qureshi, Mabood, Xie, Yufeng, Tao, Min, Tan, Xin, Xiang, Jim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013578/ https://www.ncbi.nlm.nih.gov/pubmed/24690994 http://dx.doi.org/10.3390/ijms15045508

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