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BMP4 Enhances Foam Cell Formation by BMPR-2/Smad1/5/8 Signaling

Atherosclerosis and its complications are characterized by lipid-laden foam cell formation. Recently, an obvious up-regulation of BMP4 was observed in atherosclerotic plaque, however, its function and the underlying mechanism remains unknown. In our study, BMP4 pretreatment induced macrophage foam c...

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Detalles Bibliográficos
Autores principales: Feng, Jun, Gao, Jiangfei, Li, Yuxin, Yang, Yanhua, Dang, Lili, Ye, Yuanpeng, Deng, Jingyuan, Li, Antai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013580/
https://www.ncbi.nlm.nih.gov/pubmed/24690996
http://dx.doi.org/10.3390/ijms15045536