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Synthesis and Anti-Breast Cancer Evaluation of Novel N-(Guanidinyl)benzenesulfonamides

A series of 4-(substituted)-N-(guanidinyl)benzenesulfonamides bearing biologically active pyrazole, pyrimidine and pyridine moieties were prepared and evaluated for their anticancer activity against human tumor breast cell line (MCF7). These sulfonamides showed promising activity with IC(50) values...

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Detalles Bibliográficos
Autores principales: Ghorab, Mostafa M., El-Gazzar, Marwa G., Alsaid, Mansour S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013583/
https://www.ncbi.nlm.nih.gov/pubmed/24694543
http://dx.doi.org/10.3390/ijms15045582