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Immuno-Expression of Endoglin and Smooth Muscle Actin in the Vessels of Brain Metastases. Is There a Rational for Anti-Angiogenic Therapy?

Despite ongoing clinical trials, the efficacy of anti-angiogenic drugs for the treatment of brain metastases (BM) is still questionable. The lower response rate to anti-angiogenic therapy in the presence of BM than in metastatic disease involving other sites suggests that BM may be insensitive to th...

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Detalles Bibliográficos
Autores principales: Barresi, Valeria, Branca, Giovanni, Caffo, Maria, Caltabiano, Rosario, Ieni, Antonio, Vitarelli, Enrica, Lanzafame, Salvatore, Tuccari, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013588/
https://www.ncbi.nlm.nih.gov/pubmed/24699047
http://dx.doi.org/10.3390/ijms15045663