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Cetuximab-Induced MET Activation Acts as a Novel Resistance Mechanism in Colon Cancer Cells

Aberrant MET expression and hepatocyte growth factor (HGF) signaling are implicated in promoting resistance to targeted agents; however, the induced MET activation by epidermal growth factor receptor (EGFR) inhibitors mediating resistance to targeted therapy remains elusive. In this study, we identi...

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Detalles Bibliográficos
Autores principales: Song, Na, Liu, Shizhou, Zhang, Jingdong, Liu, Jing, Xu, Ling, Liu, Yunpeng, Qu, Xiujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013599/
https://www.ncbi.nlm.nih.gov/pubmed/24714091
http://dx.doi.org/10.3390/ijms15045838