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Differential Signaling by Protease-Activated Receptors: Implications for Therapeutic Targeting

Protease-activated receptors (PARs) are a family of four G protein-coupled receptors that exhibit increasingly appreciated differences in signaling and regulation both within and between the receptor class. By nature of their proteolytic self-activation mechanism, PARs have unique processes of recep...

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Detalles Bibliográficos
Autores principales: Sidhu, Tejminder S., French, Shauna L., Hamilton, Justin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013622/
https://www.ncbi.nlm.nih.gov/pubmed/24733067
http://dx.doi.org/10.3390/ijms15046169