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Quality Control and Stability Studies with the Monoclonal Antibody, Trastuzumab: Application of 1D- vs. 2D-Gel Electrophoresis

Recombinant monoclonal antibodies (rmAbs) are medicinal products obtained by rDNA technology. Consequently, like other biopharmaceuticals, they require the extensive and rigorous characterization of the quality attributes, such as identity, structural integrity, purity and stability. The aim of this...

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Detalles Bibliográficos
Autores principales: Nebija, Dashnor, Noe, Christian R., Urban, Ernst, Lachmann, Bodo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013636/
https://www.ncbi.nlm.nih.gov/pubmed/24739811
http://dx.doi.org/10.3390/ijms15046399