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Gentamicin Blocks the ACh-Induced BK Current in Guinea Pig Type II Vestibular Hair Cells by Competing with Ca(2+) at the l-Type Calcium Channel
Type II vestibular hair cells (VHCs II) contain big-conductance Ca(2+)-dependent K(+) channels (BK) and l-type calcium channels. Our previous studies in guinea pig VHCs II indicated that acetylcholine (ACh) evoked the BK current by triggering the influx of Ca(2+) ions through l-type Ca(2+) channels,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013660/ https://www.ncbi.nlm.nih.gov/pubmed/24758923 http://dx.doi.org/10.3390/ijms15046757 |