Block of the Mevalonate Pathway Triggers Oxidative and Inflammatory Molecular Mechanisms Modulated by Exogenous Isoprenoid Compounds

Deregulation of the mevalonate pathway is known to be involved in a number of diseases that exhibit a systemic inflammatory phenotype and often neurological involvements, as seen in patients suffering from a rare disease called mevalonate kinase deficiency (MKD). One of the molecular mechanisms unde...

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Detalles Bibliográficos
Autores principales: Tricarico, Paola Maura, Kleiner, Giulio, Valencic, Erica, Campisciano, Giuseppina, Girardelli, Martina, Crovella, Sergio, Knowles, Alessandra, Marcuzzi, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013665/
https://www.ncbi.nlm.nih.gov/pubmed/24758928
http://dx.doi.org/10.3390/ijms15046843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013665/
https://www.ncbi.nlm.nih.gov/pubmed/24758928
http://dx.doi.org/10.3390/ijms15046843

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