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The synergistic effect of Mig-6 and Pten ablation on endometrial cancer development and progression

Ablation of Mig-6 in the murine uterus leads to the development of endometrial hyperplasia and estrogen-induced endometrial cancer. An additional endometrial cancer mouse model is generated by ablation of Pten (either as heterozygotes or by conditional uterine ablation). To determine the interplay b...

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Detalles Bibliográficos
Autores principales: Kim, Tae Hoon, Franco, Heather L., Jung, Sung Yun, Qin, Jun, Broaddus, Russell R., Lydon, John P., Jeong, Jae-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013686/
https://www.ncbi.nlm.nih.gov/pubmed/20418913
http://dx.doi.org/10.1038/onc.2010.126