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Systematic reviews and meta-analysis of preclinical studies: why perform them and how to appraise them critically
The use of systematic review and meta-analysis of preclinical studies has become more common, including those of studies describing the modeling of cerebrovascular diseases. Empirical evidence suggests that too many preclinical experiments lack methodological rigor, and this leads to inflated treatm...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013765/ https://www.ncbi.nlm.nih.gov/pubmed/24549183 http://dx.doi.org/10.1038/jcbfm.2014.28 |