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Systematic reviews and meta-analysis of preclinical studies: why perform them and how to appraise them critically

The use of systematic review and meta-analysis of preclinical studies has become more common, including those of studies describing the modeling of cerebrovascular diseases. Empirical evidence suggests that too many preclinical experiments lack methodological rigor, and this leads to inflated treatm...

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Detalles Bibliográficos
Autores principales: Sena, Emily S, Currie, Gillian L, McCann, Sarah K, Macleod, Malcolm R, Howells, David W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013765/
https://www.ncbi.nlm.nih.gov/pubmed/24549183
http://dx.doi.org/10.1038/jcbfm.2014.28