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p38α MAPK-mediated induction and interaction of FOXO3a and p53 contribute to the inhibited-growth and induced-apoptosis of human lung adenocarcinoma cells by berberine

BACKGROUND: Berberine (BBR), a component from traditional Chinese medicine, has been shown to possess anti-tumor activity against a wide spectrum of cancer cells including human lung cancer, but the detailed mechanism underlining this has not been well elucidated. METHODS: In this study, the effect...

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Detalles Bibliográficos
Autores principales: Zheng, Fang, Tang, Qin, Wu, JingJing, Zhao, ShunYu, Liang, ZhanYang, Li, Liuning, Wu, WanYin, Hann, Swei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013801/
https://www.ncbi.nlm.nih.gov/pubmed/24766860
http://dx.doi.org/10.1186/1756-9966-33-36